CNS: DNA Damage, autophagocytosis and Parkinson’s

Fernando Cardozo, Ph.D. (CNS, DNA damage and repair, ROS, Parkinson’s)

• Changes in neuronal populations in the nigrostriatal system as a consequence of aging or toxicological challenge
• Temporal and cellular compartmental expression of DNA repair enzymes in neuroprotective strategies
• Neuronal population changes in cell culture and in brain sections to establish either mitochondrial and/or nuclear
• Expression of DNA repair enzymes and identify the relation of organelle exposure and neuroprotection